Deep dives into the methods behind payer submissions, policy cases, and real-world studies — with the pitfalls named and the fixes shown.
Designing RWE studies that regulators and payers accept — from data source to bias assessment.
Explore RWE →Building CEA and cost-utility models — ICERs, QALYs, discounting, and probabilistic sensitivity analysis.
Explore CEA →Turning administrative claims into defensible cohorts — coding, comorbidities, and censoring.
Explore claims →Designing and analysing patient registries for long-term outcomes and safety signals.
Explore registries →Specify the trial you wish you'd run, then emulate it from observational data — cleanly.
Explore TTE → ● ToolsSize your study and check its power with the free calculators before you collect a single record.
Open research tools →A flawed cost-effectiveness model or a biased RWE study doesn't just fail review — it misdirects funding and care. The HEOR Hub exists to keep the methods honest.